Calculate route from Columbia (South Carolina, United States) to Knoxville (Tennessee, United States).

The flight distance (as the crow flies) between Columbia and Knoxville is 341.3 km.

Roadmap (route) to go from Columbia to Knoxville detailed above, you can also see the course layout on the map.

While doing trip Columbia - Knoxville by car, the calculated route ends at a distance , or more straight.